Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - GPR - CRTh2 antagonist 2

CRTh2 antagonist 2

CAS No. 780763-95-3

CRTh2 antagonist 2( —— )

Catalog No. M32868 CAS No. 780763-95-3

CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 166 Get Quote
5MG 205 Get Quote
10MG 334 Get Quote
25MG 517 Get Quote
50MG 707 Get Quote
100MG 888 Get Quote
500MG 1782 Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    CRTh2 antagonist 2
  • Note
    Research use only, not for human use.
  • Brief Description
    CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
  • Description
    CRTh2 antagonist 2 is selective and potent CRTH2 antagonist extracted from patent US20140148470A1, compound Example 1, has an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia.
  • In Vitro
    CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells) protein, also known as GPR44, is a G-protein coupled receptor (GPCR) which is amongst other ligands most strongly activated by prostaglandin D2 (PGD2). PGD2 is a product of prostaglandin D2 synthase (PTGDS).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    GPR
  • Recptor
    GPR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    780763-95-3
  • Formula Weight
    474.94
  • Molecular Formula
    C26H23ClN4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (263.19 mM; Ultrasonic )
  • SMILES
    CN(C)c1nc(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)nc(Cl)c1CC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Andreas Schnapp, et al. Pyrimidine compounds for treating hairloss. US20140148470A1.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • TAK-875 hemihydrate

    Fasiglifam (TAK-875) is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line.

  • SB271046

    SB271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9, exhibits 200-fold greater selectivity over other 5-HT receptor subtypes.

  • DJ-V159

    DJ-V159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A).

Sign In Join Free